[syndicated profile] theatlantic_health_feed

Posted by Nicholas Florko

Gas-station weed was never supposed to exist. And yet, convenience stores across the country—even in states where marijuana is illegal—sell a trove of fizzy drinks, vape pens, and confections all promising to get you high. My neighborhood liquor store has an entire cooler full of weed drinks, including a seltzer aptly named Bong Water, a can of which has 25 milligrams of THC. About five milligrams of that chemical, which is the main psychoactive component in marijuana, will make the occasional weed user feel a light buzz. If that’s not enough for you, you might be able to buy a vape pen with 5,000 milligrams at your corner store.

These products are available because Congress messed up. In 2018, it passed a bill that was meant to support farmers by allowing them to grow hemp—essentially, weed bred with minimal THC—for industrial uses such as paper, insulation, and even guitars. In the process, it also accidentally created a new industry of intoxicating hemp products that are virtually indistinguishable from those made using traditional marijuana, except for the fact that they’re federally legal.

If Congress has its way, however, such products could soon disappear. Tucked into the funding legislation that ended the government shutdown was a bill that would outlaw virtually any THC product not sold at a licensed dispensary—a mortal threat to the industry that’s brought Americans Trips Ahoy cookies and THC-infused Dorito knockoffs.

The particulars of the current loophole are wonky, but the law allows companies to sell any hemp product that doesn’t contain more than 0.3 percent THC by dry weight. A company selling a 40-gram cookie, for example, could add 100 milligrams of THC and still be under that limit. Crucially, this applies to products sold anywhere in the country. Kansas hasn’t legalized either recreational or medical cannabis, but as I’ve previously reported, when I went to Topeka in 2023, I was able to find intoxicating hemp products in 10 shops within an afternoon. In a state like Illinois, where legal marijuana abounds, the distinction between weed sold in licensed dispensaries and hemp sold at convenience stores might seem pedantic. But dispensaries have to follow rules meant to keep users safe, and they must keep the product cordoned off from people under 21. Sellers of THC-containing hemp products don’t have to follow the same rules. Technically, many states don’t even specify a minimum age to buy these products.

The downsides of this system were immediately apparent. In a recent nationwide survey, approximately 11 percent of high-school seniors reported trying hemp products that feature Delta 8, one of the mind-tweaking compounds found in marijuana. Mitch McConnell, who championed the amendment closing the loophole, said on the Senate floor during the debate over the bill that passing it would “keep these dangerous products out of the hands of children.” Plus, many of these technically legal hemp products are filled with potentially dangerous synthetic compounds. Delta 8, for example, naturally occurs in marijuana only in very small amounts, so the substance added to vapes and drinks is typically created by chemically manipulating CBD, a more prevalent compound in the plant. The FDA has warned that this process may include “potentially unsafe household chemicals” and may be done “in uncontrolled or unsanitary settings, which may lead to the presence of unsafe contaminants or other potentially harmful substances.”

[Read: The new war on weed]

Now, after seven years, Congress has decided that enough is enough. Under the new funding bill, any product with more than 0.4 milligrams total THC—virtually nothing—would be considered a Schedule I narcotic, just like heroin, LSD, and regular old marijuana. The law will for the most part not affect dispensaries in states that have legalized weed, but it will make more than 95 percent of the current hemp market illegal, Jonathan Miller, a lobbyist for the industry group U.S. Hemp Roundtable, told me. And that’s the point: I asked Kevin Sabet, who runs an anti-marijuana group that lobbied for the new legislation on Capitol Hill, what successful implementation would look like. “A lot of the major players out of business,” he told me.

The new legislation doesn’t go into effect for a year, and already, the hemp industry is trying to persuade lawmakers to call off the crackdown. When I spoke with Miller on Tuesday, he told me that he was set to discuss the issue with an influential member of Congress the next day. The Hemp Roundtable, which spent $320,000 lobbying Congress last year, is hoping to persuade lawmakers to abandon the 0.4-milligram THC limit for something more workable—perhaps five or 10 milligrams, Miller told me. Ed Marszewski, the president of Marz Community Brewing Co., which makes Bong Water, told me that his company also wants regulations on serving sizes for hemp products, as well as age restrictions and safety testing.

Hemp companies might also wait to see how the new law will be enforced before taking any dramatic action. Despite the 2018 hemp loophole, selling food to which THC or CBD has been added is unequivocally prohibited by the FDA. However, the agency has typically gone after only those companies making unsubstantiated health claims or marketing their products to kids, Jonathan Havens, a cannabis attorney at the law firm Saul Ewing, told me. Since 2018, roughly 100 companies have received warnings from the FDA for selling cannabis-containing products. The industry, clearly, has kept on making its forbidden treats.

[Read: Marijuana is too strong now]

The question is whether the status quo changes in 2027, given the higher stakes. Selling a Schedule I narcotic typically carries a stiffer penalty than violating FDA rules does. But the Drug Enforcement Administration doesn’t currently have the resources to surveil every gas station, smoke shop, and liquor store in the country, and closely policing those settings would mean taking agents off more serious cases, Jim Crotty, a former DEA official, told me. (The DEA did not respond to a request for comment.) The federal government hasn’t shown a willingness to police local cannabis sales in the past: Licensed marijuana dispensaries are technically illegal under federal law too, but the feds have typically not interfered with shops that abide by state law. A similar scenario could play out with hemp products, Douglas Berman, the executive director of the Drug Enforcement and Policy Center at Ohio State University, told me.


Proponents of this new law may hope that the days of hemp gummies and seltzers are limited. But passing a policy like this is easy compared with the work required to enforce it. Americans may soon find out if the government is up to the job.

[syndicated profile] icanhascheezburger_feed

Posted by Ayala Sorotsky

Some days are just cold. Not just outside, but inside your soul a little bit too. The kind of days where you need something soft, something gentle, something warm enough to thaw you from the inside out. And if there's one thing on this planet we know is able to melt the frost off your mood, it's cats - the soft, sweet, fluffy feline heart-heaters they are.

Cats don't even have to try to be comforting. One tiny paw draped over your arm? Instant warmth. A slow blink from across the room? Emotional hot chocolate. A purr that rumbles like a teeny tiny tractor engine? That's basically therapy. Even their drama is adorable - like when they flop dramatically on the floor because they simply must be petted this very moment or they will perish.

And on days when the world feels chilly or heavy or just… meh, cat memes come in like little pockets of sunshine. A soft boopable nose here, a fluffy loaf there, a cat making questionable life choices in a cardboard box - all of it working together to warm your heart like a cozy blanket straight from the dryer. So grab that morning warm drink and let this batch of fluffy feline funnies snuggle right into your day. Because the weather might be cold, but cats (and cat memes) are pure, sweet warmth.

[syndicated profile] cbc_topnews_feed
A woman in a gown wears a crown, surrounded by other women in gowns

Fátima Bosch Fernández wiped away tears as she was crowned Miss Universe 2025 in Bangkok on Friday. It was a dramatic victory for Bosch, 25, in a pageant plagued by controversy and chaos — perhaps even more so than usual.

flo_nelja: (Default)
[personal profile] flo_nelja
Fics are unanoned!


Title : Less than Death
Author : Nelja
Fandom : Trigun
Characters/Ships : Legato->Knives
Genre : Angst
Summary : After July, Legato is waiting for Master Knives to wake up.
Rating : M
Disclaimer : This belongs to Yasuhiro Nightow!
Word Count : ~1300
Warnings : A bit of gore, thoughts of rape, very creepy, very vague mention of potential genocide, the usual for this ship.

( Link to AO3 )



And I got a fic for the same ship, same moment in the timeline, we wrote for each other. Shared ids!

carnivorous and lusting by andthentherewere_none
Sunburst. Legato dashed his hand across his eyes, then sank into the nest of wires. They crossed themselves like a bed of snakes. Protecting the sweet fruit that hadn't ripened yet. Their thick bodies supported Legato as he crossed the perilous distance and came to lay next to his savior.
"I've found him."
He spoke gently into Knives' ear as his voice slipped and layered over his breath.
"The one who put you here. I know you have your own ways to make this right." Legato felt heat funneling into his body from the gut. It spread outward, like a stain on cloth. He was stained. Human and vile. His imperfection couldn't be helped. When in the presence of a perfect being, how could he even pretend to be unsullied by his nature. He ignored the stiffness in his pants and pressed his lips closer to Knives' ear. His voice ghosting into him, hopefully touching the mind asleep beneath. "Your rebirth will be soon, when this body, too destroyed, will be returned to full glory. To witness it…" He shivered. "I will be there. My master. At your side when you return fully to us."

More on Rewiring Democracy

Nov. 21st, 2025 07:07 pm
[syndicated profile] schneiersecurity_feed

Posted by Bruce Schneier

It’s been a month since Rewiring Democracy: How AI Will Transform Our Politics, Government, and Citizenship was published. From what we know, sales are good.

Some of the book’s forty-three chapters are available online: chapters 2, 12, 28, 34, 38, and 41.

We need more reviews—six on Amazon is not enough, and no one has yet posted a viral TikTok review. One review was published in Nature and another on the RSA Conference website, but more would be better. If you’ve read the book, please leave a review somewhere.

My coauthor and I have been doing all sort of book events, both online and in person. This book event, with Danielle Allen at the Harvard Kennedy School Ash Center, is particularly good. We also have been doing a ton of podcasts, both separately and together. They’re all on the book’s homepage.

There are two live book events in December. If you’re in Boston, come see us at the MIT Museum on 12/1. If you’re in Toronto, you can see me at the Munk School at the University of Toronto on 12/2.

I’m also doing a live AMA on the book on the RSA Conference website on 12/16. Register here.

full_metal_ox: A gold Chinese Metal Ox zodiac charm. (Default)
[personal profile] full_metal_ox posting in [community profile] metaquotes
[personal profile] dissectionist: Back in MY DAY, we had to read Penthouse Forum letters into a tape recorder and put the resulting tape into a first-gen Teddy Ruxpin. Nowadays kids don’t even have to work to turn their teddy bear into a creep.

Context recounts FoloToy’s Shock and Surprise at what happens when you feed a kid’s toy OpenAI.

Neither Present Nor Accounted For

Nov. 21st, 2025 09:16 am
lydamorehouse: (ichigo irritated)
[personal profile] lydamorehouse
 Sorry, everybody.

It's actually been a really big week for me, being my birthday week, but I seem to have completely forgotten to update you all on any of it. I have about fifteen minutes before I need to head out, so let's see what I can tell you about in that amount of time.

I turned 58 on Tuesday. 

I have never been one of those people who hates birthdays or the idea of growing older. I love every single birthday (with the sole exception of the one that I spent driving back from Indiana.) But, generally, I am all about starting to celebrate my birthday as soon as possible and, this year, I started on November 3 (my birthday is the 18th). One of the things that I very expressly asked my wife for was time to game. Normally we fuss a bit because, if I had my way, I'd be running D&D every single weekend that my players was available.  So, for November, I've played D&D every single weekend so far--which has been tremendous fun. It's come to a close, however, as the Thanksgiving prep is in full swing. 

Shawn always takes my birthday off work. She also almost always takes her own birthday off, too, as did I when I was working. In fact one of the funniest conversations I ever had with a boss was when I was working as a itenerent library page for Ramsey County Library. My boss at the time, Lee Ann, was a fellow Scorpio. She also used to call all the pages to see where and when they'd be available. The 18th was floated for me and I just said, "Sorry, that's my birthday." She seemed stunned. She said, "Well, tomorrow is my birthday and I'm working," and I said, "That sounds sad. You should take your birthday off." Apparently, this is not something that regularly occurs to adults. Lee Ann seemed very stunned and afronted. But, I've long embraced the fact that I'm not a normal adult.

Side story, but part of birthday week for me has been getting to go get fancy coffee in the mornings. I discovered that one of the barista at Claddaugh really, really loves rocks. So, I've started carrying rocks in my pockets again just to show her the ones I've collected. Yesterday, I pulled out the Thomsonsite that I have from our trips to Bearskin and showed it off. Other people were interested so a bunch of adults started oohing and ahhing over cool rocks. And it reminded me of that meme that goes around with the guy who is sad because the worst part of being an adult is that no one ever (shows you a cool rock, is one version, or) asks you your favorite dinosaur. So, we very quickly all started sharing our favorite dinosaurs, as well. Take that, adulthood!  You can't diminish my love for cool rocks and dinosaurs!  NEVER GO QUIETLY INTO THE LONG DARK! LOVE ROCKS! LOVE DINOSAURS!

The other thing I love to do is go out to eat. I am especially fond of breakfast or brunch out. I love me a good greasy spoon, too. I have had my family take me out to the Egg & I, but this year we went to Day by Day. which is slightly less grease and more hippy/recovery community. I pushed out the boat (and as Shawn has been adding lately, and got into it! Because you don't want to "push out the boat" and then "miss the boat") and had their buscuits and gravy. Not a safe meal for a 58 year old, but look at me, living on the edge!  Do I know how to party, or what?

We also went out for dinner, which, in our family, is borders on insanity. Like, we were seriously living it up. Dinner was Taste of India out in Maplewood, a place that I've been going to for my birthday for decades. 

The only pall on the day was the fact that I forgot my cell phone at home and so I missed the MONARCA text about the Federal action in Midway. It's probably just as well. Pepper spray got deployed and no one wants to be pepper sprayed for their birthday. (I mean, maybe [personal profile] sabotabby does?) I did feel bad for missing it as my friends [personal profile] naomikritzer and [personal profile] resolute were there doing the good work.

So that's me? How's you?
[syndicated profile] cbc_topnews_feed
A man with a beard and turban standing on Parliament Hill.

One of three Sikh separatists arrested for firearms offences has had all charges against him dropped. Jagdeep Singh of New York was arrested in September along with two other men. One of them, Inderjit Singh Gosal, replaced Hardeep Singh Nijjar as leader of the Sikh independence referendum campaign in Canada following Nijjar's 2023 assassination.

(no subject)

Nov. 21st, 2025 12:14 pm
ororo: (Default)
[personal profile] ororo posting in [community profile] holiday_wishes
Hi everyone!

Whatever you might be celebrating, may it be joyful. For me, that’s the days getting longer at the Winter Solstice.


I’ve been participating for a few years and happy I’m able to do so again this year. I'm a woman of a certain age, closing in on Old Bathood, and live in NYC

  • Donations to your public library
  • Donations to your state or local Civil Liberties Union
  • If you’re a reader, please rate and review the last book you read or the book you’re currently reading. These ratings and reviews are what allows algorithms to recommend the books to others
  • My Amazon wishlist is here. These are all fun things, nothing over $15.
  • Donations to your local rabbit rescue
  • Recommendations for a good spica splint that immobilizes the wrist as well as the thumb.I have DeQuervain's, which means the tendors around my thumb are a bit borked. I don't need anyone to purchase the splints, I have funds set aside for medical things to do that, but the splints I have only immobilize my thumb.
  • Your favorite air fryer recipes—please note my air fryer is a small one, so I can’t do recipes that need things on multiple levels/racks
  • Tea! Loose or bagged. I like white, green, oolong, and blacks, though not pu-ehr.
  • Anime recommendations. I am a huge fan of Full Metal Alchemist, I recently enjoyed the first season of the Apothecary Diaries. Girls/Women as weapons are cool, so are mecha. I prefer the romance understated and most of the sex offscreen
  • DoorDash gift cards for those nights when work or the news takes too much out of me to cook


Thank you!

Contact Info )

Check-In Post - Nov 21st 2025

Nov. 21st, 2025 07:03 pm
badly_knitted: (Get Knitted)
[personal profile] badly_knitted posting in [community profile] get_knitted

Hello to all members, passers-by, curious onlookers, and shy lurkers, and welcome to our regular daily check-in post. Just leave a comment below to let us know how your current projects are progressing, or even if they're not.

Checking in is NOT compulsory, check in as often or as seldom as you want, this community isn't about pressure it's about encouragement, motivation, and support. Crafting is meant to be fun, and what's more fun than sharing achievements and seeing the wonderful things everyone else is creating?

There may also occasionally be questions, but again you don't have to answer them, they're just a way of getting to know each other a bit better.


This Week's Question (courtesy of [personal profile] ysabetwordsmith): When learning a new art or craft, do you prefer level-grinding the basics, skipping ahead to the cool techniques, or a mix of both?


If anyone has any questions of their own about the community, or suggestions for tags, questions to be asked on the check-in posts, or if anyone is interested in playing check-in host for a week here on the community, which would entail putting up the daily check-in posts and responding to comments, go to the Questions & Suggestions post and leave a comment.

I now declare this Check-In OPEN!



Random Roman Remains

Nov. 21st, 2025 06:57 pm
purplecat: Black and White photo of production of Julius Caesar (General:Roman Remains)
[personal profile] purplecat

The remains of Hadrian's Wall on the right snake over a rise down and then up over the next rise.  The remains of a square building abut the wall close to.
A milecastle on Hadian's Wall
malurette: (mélusine)
[personal profile] malurette posting in [community profile] glyfic
Titre : Par sécurité
Auteur : [personal profile] malurette
Base : Claudine à l'école
Personnages/Couple : Aimée/Mlle Sergent
Genre :
Gradation : PG / K+
Légalité : propriété de Colette, je ne cherche ni à tirer profit ni à manquer de respect.

Prompt : 25 ans/des centaines de fandoms/little troll
Nombre de mots : 100

Elle n'est pas exactement une femme entretenue puisqu'elle continue à donner la classe dans cette école mais... )
[syndicated profile] in_the_pipeline_feed

Here’s a phenomenon - yet another one - that never crossed my mind before. It’s long been known that enzymes that catalyze proteolysis (cleavage of peptide bonds) can, under certain circumstances, catalyze the reverse reaction of peptide bond formation. Folks who have had to think about chemical kinetics will immediately realize that those conditions would include high concentrations of the two cleavage products and low concentrations of the longer protein substrate, an example of Le Chatlier’s principle in action. It’s also an example of the principle of Microscopic Reversibility in action, too: the chemical steps are the same whether you run things forwards or backwards. That doesn’t mean those steps are always thermodynamically feasible, of course - the energies involved (with both enthalpic and entropic contributions) might be too great a barrier to run backwards very easily, as in unburning a piece of wood back from a cloud of soot and hot gases. Fire is not a good example of an equilibrium process, but peptide bond breakage and formation is a lot closer to balancing on a knife edge than combustion is.

This recent preprint suggests, though, that this “reverse proteolysis” is happening under physiological conditions, particularly with cysteine-based cathepsin enzymes. And it’s not just re-formation of the proteins that have just been cleaved (although that must be happening, too). No, you get mix-and-match combinations of various proteins to generate species that were certainly never coded for in the genome. And on top of that, you can even spot chimeras between human proteins and bacterial or viral ones (!)

Now, some species of this sort have been reported before (in reports going back to at least 2004) but this new work suggests that it’s a much more common process than anyone realized, one with implications for immunity and perhaps other cellular processes as well. Recall that antigen proteins are displayed to the immune system via the major histocompatibility complex, and that these antigens are cleaved from larger proteins via degradation. Displaying weirdo newly assembled protein sequences from this chemical splicing route could cause some real effects downstream. This could, for example, be one of the links between prior infections and later autoimmune disease, through those human/pathogen hybrid proteins.

The authors here shore up that connection by showing that auto-antigenic peptides implicated in Type I diabetes can be produced by cathepsins running in reverse, and that proteins that have been modified by citrullination (on arginine residues) seem to undergo the process more readily. That sort of Arg modification is already known to be over-represented in autoimmune antigens. In addition, the cathepsin enzyme subtypes that are most dominant in immune tissues (such as inside macrophages) seem to be the best at producing such splicing hybrids. These reverse reactions are also more prevalent at closer to neutral pH, which suggests that lysosomal dysfunction (where cathepsins and other enzymes normally work in an acidic environment) might be a source of increased neo-peptides.

Overall, it seems that we’re going to have to learn to deal with these species, and to study them in the context of both normal conditions and in infectious disease. Acute viral infections might well be producing waves of human/viral protein hybrid species, and we can’t expect them all to be silent! 

pegkerr: (candle)
[personal profile] pegkerr
You know, I do my best to just live my life and be a brave little toaster, but this week, it's just felt like...a lot.

I need to get a new car. Mine is twenty-five years old. And I don't know where or how to start. Will I be able to afford anything decent?

Pain continues. The physical therapist has ordered me to use a cane. I have to use it in my (non-dominant) left hand, the one with arthritis, and just manipulating it with that hand is difficult enough that I have to start using my arthritis brace on that hand again.

I've also been told to wear an IS brace, a velcro strap that goes around my hips. Weirdly enough, it gives me nausea. Constantly.

Medical appointments. So. Many. Medical. Appointments.

All of this makes it difficult to exercise. And I NEED to exercise. I got the results of my bone scan this week, and my osteopenia is continuing to get worse. I need to get into the gym and lift weights and I'm not doing so, and so I'm beating myself up about it.

The news. Need I say more?

Christmas is looming, and the thought of preparing for the holidays is daunting.

I'm about to retire, and I am struggling with uncertainty about what it is going to look like. (Will I have enough money is giving me constant low-grade anxiety)

Rob's 70th birthday was this past week.

Both of the girls have been sick and stressed. Delia's internship is about to end, and she doesn't know where she will find another job.

On Wednesday, I had to sit through a meeting that droned on for an hour and a half. I kept standing up and sitting down again. I was so obviously uncomfortable that my coworkers sent me home, and I spent the rest of the day with the covers literally pulled over my head.

I'm sorry. I'm complaining, and I truly don't like that. I don't feel depressed, exactly? But I don't feel at my best, shall we say.

Image description: Background: a light-filled doorway in a room with gray peeling paint. Superimposed over it: a semi-transparent image of a woman's face with eyes closed, strands of hair blowing over her eyes. Lower center: a statue with green patina of a woman, holding her hand to her forehead. Upper left corner: a dried leaf clings to a twig.

Melancholy

46 Melancholy

Click on the links to see the 2025, 2024, 2023, 2022 and 2021 52 Card Project galleries.

November 2025

S M T W T F S
       1
23 4 5678
9 101112131415
16171819202122
23242526272829
30      

Most Popular Tags